Food grade Sodium Hyaluronate
The body in embryonic period has the highest HA content, but it gradually reduced after birth. HA content varies with each individual even among the crowd of the same age. Reduction of HA content will directly lead to skin ageing and functional decaying. For example, HA content significantly reduced in the progeria patients.
There is still many limitations for the external use of HA on skin , which can only work as lubrication and water retention.. However, the oral use of HA can increase endogenetic HA level through digestion and absorption, which makes skin moist, glossy and elastic.
HA also plays an important role of water retention and lubrication in other tissues and organs, such as joint cavity, blood vessel, heart and brain. Decrease of HA level of these tissues can result in arthritis, arteriosclerosis, pulse disorder and brain atrophy. Oral HA can restore the normal content of HA in body and delay apolexis and make the body energetic.
At present, HA is widely applied to health and beauty products in the developed countries, such as America, Japan and Europe. It is greatly welcomed by the consumers.
Characteristics
White or almost white, very hygroscopic grain or powder, without odor, turn to clear solution when dissolved in water; insoluble in ethanol,
Cosmetic Grade Sodium Hyaluronate
HA is a natural biotic component widely presents in skin and other tissues. It has outstanding moisturizing effect, thus called Natural Moisturizing Factor (NMF) in the world. HA is the best component used in cosmetics for moisturizing from the nature.
When it is applied to skin, macromolecular HA can form a thin layer permeable to air, keeping the skin smooth and moist and further protecting it from bacteria, dust and ultraviolet rays, while micromolecular HA can penetrat into corium, enlarging blood capillaries slightly, promoting blood circulation, improving intermediary metabolism and nourishment-absorbing ability of skin, thus eliminating wrinkles, increasing skin's elasticity and delaying its aging. In addition, HA can further hyperplasia of epidermic cell, clean oxygen-derived free radicals, prevent and rehabilitate skin injuries. Its aqueous solution has very high viscosity which can make water become thicker. Cream made by emulsifying HA with oil is fine and even, homogeneous with stable emulsifiction.
HA is the best natural moisturizing component used in high-end cosmetics. Thanks to it’s good compatibility, HA can be added to almost any beauty cosmetics, such as cream, lotion, astringent, essence, facial cleanser, shower gel, shampoo, hair conditioner, mousse and lip stick. In most cases, the dosage is around 0.05%-0.5%.
LMW Grade Sodium Hyaluronate
Hyaluronic Acid (HA) is a mucopolysaccharide composed of repeated disaccharide units of N-acetylglucosamine and glucuronic acid. The commercial HA is commonly a sodium form, called sodium hyaluronate. HA is widely presents in the extracellular matrix of animal tissues and vitreous humor. Its main physiological function is water retention and lubrication.
Low molecular weight sodium hyaluronate (LMWHA) can penetrate dermis to be absorbed easily by the skin. By improving blood circulation, regulating skin metabolism and ameliorating skin nutrition, LMWHA can prevent the skin aging and maintain the collagen function.
LMWHA is particularly useful in beauty parlors because of its character of penetrating dermis easily. Imported by skin conditioners with the assistance of low voltage impulse or heat, LMWHA can improve the generation of new cells and resist aging so as to let skin feel its true value.
HA in human body is high molecular weight substance. LMWHA can be synthesized into HMWHA after being absorbed by body, so the amount of entogenous HA increases. The nourishing of LMWHA acts on the whole body from the dermis to the epidermis.
High molecular weight grade Sodium Hyaluronate
Pharmacy: injectable hyaluronic acid can be used in ophthalmologic operation, such as: cataractsurgery and corneal transplantation.
Hyaluronic acid was injected into joint cavity of arthritic patient as an antarthritic of lubricant.
Research show that hyaluronic acid injection on peritoneum surface or injuries portion can effectively reduce peritoneum or tendon adhesion. Fair biocompatibility with ocular tissue, hyaluronic acid was used to produce gutta.
Cosmetics: Hyaluronic acid is called Natural Moisturizing Factor with crease resistant, skin repair and sunscreen function. It is a component of most of top grade cosmetics.
Health food and food material
As human embryonic period the hyaluronic acid level reaches peak value, after birth the level come down gradually. Hyaluronic acid level in progeria patient unconventionally decline. Oral administration hyaluronic acid make skin smooth and lustrous and elastic. Also in tissue and organ such as heart, vessel, brain, cavum articulare and so on. Hyaluronic acid supplied can be taken orally, thus reduce occurring of arteriosclerosis, anencephalotrophia and arthritis, delaying senility and makes people full of beans.