China (Mainland)
Chondroitin sulfate CAS NO.9007-28-7
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- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
99(0-25)Kilogram99(1-1000)Kilogram
- Product Details
Keywords
- Chondroitin sulfate
- 9007-28-7
- USD$1/KG,IN STOCK
Quick Details
- ProName: Chondroitin sulfate
- CasNo: 9007-28-7
- Molecular Formula: C13H21NO15S
- Appearance: powder
- Application: chemical
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Day
- Purity: 85.0-99.8%
- Storage: keep in dry and cool condition
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
Product Name: Chondroitin sulfate
Synonyms: Chondroitin sulfate (cow);Chondroitin Sulfate, Bovine Trachea;poly-1(2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose;Bovine chondroitin sulfate;Chondroitin sulfate (cattle);Chondroitin sulfate (Sha Yu);CSO;chondroitinpolysulfate
CAS: 9007-28-7
MF: C13H21NO15S
MW: 463.36854
EINECS: 232-696-9
Product Categories: Inhibitors;-;APIs;Nutritional Supplements;Nutritional fortification substances;Glycosaminoglycan;Biochemicals Found in Plants;Carbohydrates;GlycosaminoglycanGlycan Component Classes;Glycosaminoglycans;Glycosaminoglycans and Proteoglycans;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File: 9007-28-7.mol
Chondroitin sulfate Structure
Chondroitin sulfate Chemical Properties
storage temp. Store at RT.
form Powder
color White to Off-white
Water Solubility Soluble in water.
CAS DataBase Reference 9007-28-7(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
TSCA Yes
HS Code 39139000
MSDS Information
Chondroitin sulfate Usage And Synthesis
General Description At room temperature, it is a white powder, odorless, tasteless. It has a strong ability of water absorption. It is highly soluble in water to become a solution with high viscosity. It become unstable upon higher temperatures or acidic condition, primarily being deacetylated or being degraded into monosaccharide or smaller molecular-weight polysaccharide. It is not soluble in organic solvent like ethanol, acetone and ether. Its salt is quite stable to heat without being destroyed when heated to 80 °C.
Chondroitin sulfate is a mixture of acid mucopolysaccharides extracted from the cartilage of pigs, cattle, chicken, and shark cartilage. According to their differences in chemical composition and structure, it is divided into A, B, C, D, E, F, H, etc. It mainly contains mucopolysaccharides such as chondroitin sulfate A and chondroitin sulfate C. Both chondroitin sulfate A and C contain D-glucuronic acid and 2-hydroperoxy group-deoxy-D-galactose, and contain equal amounts of acetyl and sulfuric acid residue. The only difference between them is the different position of sulfuric acid ester on the hexosamine residues. Chondroitin sulfate A can enhance the activity of lipase, causing the decomposition of triglyceride in chylomicron so that the blood will become clean due to the decrease of chylomicrons. It has anticoagulant and antithrombotic effect, and thus is clinically used for the treatment of coronary artery disease, elevated blood lipids and cholesterol, angina, neuralgia, myocardial ischemia and myocardial infarction embolism. It can also be used for prevention and treatment of hearing disorders and migraine caused by streptomycin, neuropathic pain, elderly pain of shoulder, backache, arthritis and hepatitis and skin cosmetics. It is reported that chondroitin sulfate can also be effective on improving and repairing of articular cartilage, synovium, keep the lubrication between the joints cartilages and making it elastic, alleviating joint pain and inflammation. Moreover, it also has special efficacy on symptoms located in tendons, ligaments, and diaphragm.
Chondroitin sulfate is also an important component of eye tissue. It can boost the water metabolism in corneal, improve the microcirculation, protect the cornea and promote the repair function of corneal tissue. It can also form a protective form in the corneal surface to prevent water evaporation which can effectively relieve visual fatigue and symptoms of dry eye; In additions to its anti-bacterial and anti-inflammatory effect, taurine can also participates in a lot of physiological activities in eye tissue and promote metabolism, alleviate visual fatigue.
Function 1. Chondroitin sulfate is mucopolysaccharides-class substance extracted from animal cartilage. It has an important role in prevention and treatment of cardiovascular disease, joint disease, and currently is an important biochemical product on the market.
2. As a health food or drugs, chondroitin sulfate has been long used to prevention and treatment of coronary heart disease, angina, myocardial infarction, coronary atherosclerosis, myocardial and ischemia with no significant side effects. It can significantly reduce the incidence and mortality of coronary heart disease. Long-term clinical application finds that the deposited fat can in the walls of arteries and veins can be effectively reduced or removed, which can significantly lower plasma cholesterol level, and thus preventing the formation of atherosclerosis.
3. Chondroitin sulfate can also be used for the treatment of neuropathic pain, nerve migraine headaches, joint pain, arthritis and scapular joint pain, pain after abdominal operation.
4. It can be used for prevention and treatment of hearing impairment caused by streptomycin, and hearing difficulties, tinnitus caused by a variety of noise with a significant effect.
5. It also has adjuvant therapy on chronic nephritis, chronic hepatitis, keratitis and corneal ulcers.
6. It is reported in recent years that, the chondroitin of shark cartilage has anti-tumor effect. In addition, chondroitin sulfate is also used for cosmetics and as healing agent of traumatic wound. Chondroitin sulfate is a kind of acidic mucopolysaccharides as an important component of ocular tissues. It can promote and improve the water metabolism of the cornea which is suitable for treating eye fatigue and dry eye syndrome.
Details
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.
At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.
Henan Coreychem co., LTD. is committed to provide cost effective chemical service to the global fine chemical industry product development agencies; we adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.