Castor oil CAS NO.8001-79-4

Product Name: Castor oil

Synonyms: 2,3-bis[[(Z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (Z)-12-hydroxyoctadec-9-enoate;CASTOR-OIL, PH EUR;CASTOR OIL USP;ImmersionOilForMicroscopy-OpticallyClear,Non-Fluorescent;CASTOR OIL, PHARMA;CASTOR OIL, COLD PRESSED;Castor oil, Eur. Pharm. Grade;Castor

CAS: 8001-79-4

MF: C57H104O9

MW: 933.43026

EINECS: 232-293-8

Product Categories: Alphabetical Listings;C-DFlavors and Fragrances;Essential Oils;Flavors and Fragrances;OilsEssential Chemicals;Routine Reagents;USP;Biochemicals Found in Plants;OilsBiochemicals and Reagents;Lipids and Related ProductsBiochemicals and Reagents;Core Bioreagents;Lipids;Oils;Research Essentials;-

Mol File: 8001-79-4.mol

Castor oil Structure

Castor oil Chemical Properties

Melting point -10 °C

Boiling point 313 °C(lit.)

density 0.955 g/mL at 25 °C

refractive index n20/D 1.478(lit.)

FEMA 2263 | CASTOR OIL (RICINUS COMMUNIS L.)

Fp >230 °F

solubility Miscible with chloroform, diethyl ether, ethanol, glacial acetic acid, and methanol; freely soluble in ethanol (95%) and petroleum ether; practically insoluble in water; practically insoluble in mineral oil unless mixed with another vegetable oil.

form Viscous Hygroscopic Liquid

color Clear almost colorless or slightly yellow

Specific Gravity 0.961

optical activity [α]20/D +5°, c = 5 in ethanol

Water Solubility <0.1 g/100 mL at 20 ºC

FreezingPoint -10℃

Merck 14,1898

Stability: Stable. Combustible. Incompatible with strong oxidizing agents. May be light sensitive.

NIST Chemistry Reference Castor oil(8001-79-4)

EPA Substance Registry System Castor oil(8001-79-4)

Safety Information

Safety Statements 24/25

WGK Germany -

RTECS FI4100000

F 10

TSCA Yes

HS Code 15153090

Hazardous Substances Data 8001-79-4(Hazardous Substances Data)

MSDS Information

Provider Language

Castor oil English

ACROS English

SigmaAldrich English

ALFA English

Castor oil Usage And Synthesis

Chemical Properties pale yellow viscous liquid

Chemical Properties Dehydrated castor oil is a castor oil from which approximately 5% of the chemically combined water has been removed. Therefore it has drying properties similar to those of Tung oil. Dehydration is carried out by heating the oil in the presence of catalysts such as sulphuric acid, phosphoric acid, clays and metal oxides. Dehydrated castor oil is a yellow oily liquid with characteristic odour.

Standard specifications

commercial grade pale grade special grade

refractive index (20°C) 1,482 - 1,483 1,482 - 1,483 1,482 - 1,483

specific gravity (15°C) 0,982 - 0,933 0,982 - 0,933 0,982 - 0,933

viscosity (25°C) Poise 1,6 - 2,8 1,6 - 2,8 1,6 - 2,8

viscosity Gardner scale G – I G – I G – I

colour max. 8 max. 6 max. 5

acid value mg KOH/g max.6 max. 4

iodine value (Wijs) g I2/100g min. 130 min. 130 min. 130

hydroxyl value mg KOH/g max. 25 max. 20

Chemical Properties Castor oil is a clear, almost colorless or pale yellow-colored viscous oil. It has a slight odor and a taste that is initially bland but afterwards slightly acrid.

Chemical Properties Castor oil is obtained by cold expression of kernels, which contain 45 to 50% oil. It has a faint, mild odor and a bland characteristic taste.

Chemical Properties Castor tree is a common annual ornamental whose native habitat is in the West Indies. The tree grows up to 5 m high. The leaves are large, alternate, peltate, palmately 5- to 12-lobed; the petiolate has conspicuous glands. The seeds are ovoid with a large caruncle; the endosperm is fleshy and oily. The plant thrives in rich, well-drained, sandy or clay loam; it is grown in India and the United States. Castor beans have been cultivated from the earliest times for the oil of the seeds, the only part used. Commercially, the oils and cakes are obtained by cold expression or are steam treated to denature the toxin.

Physical properties The oil is a pale-yellowish or almost colorless, transparent viscid liquid. It is soluble in alcohol, and is miscible with absolute alcohol, glacial acetic acid, chloroform and ether.

Uses Dehydrated castor oil is an unique drying oil, which imparts good flexibility, fine gloss, toughness, adhesion, chemical and water resistance to the dry paint film with non-yellowing properties. DCO is a very suitable and even better substitute for Linseed oil. Paints with DCO are super white and offer superior finish.

Dehydrated castor oil is used as a primary binder for house paints, enamels, caulks, sealants and inks. In “cooked” varnishes it is combined with all the basic resins, rosins, rosin-esters, hydrocarbons and phenolics to produce clear varnishes and vehicles for pigmented coatings. DCO is also used in the manufacturing of lithographic inks, linoleum, putty and phenolic resins.

DCO is used with phenolics to obtain fast drying coatings with maximum alkali resistance as required in sanitary can lining, corrosion resistant coatings, traffic paints, varnishes, ink vehicles, wire enamels, aluminium paint appliance finishes and marine finishes.

DCO is also used to obtain fast kettling rate which gives lighter colour and lower acid varnishes.

Uses Castor Oil is a release and antisticking agent used in hard candy pro- duction. its concentration is not to exceed 500 ppm. it is used in vitamin and mineral tablets, and as a component of protective coatings.

Uses antidiabetic

Uses castor oil is a highly emollient carrier oil that penetrates the skin easily, leaving it soft and supple. It also serves to bind the different ingredients of a cosmetic formulation together. Castor oil is high in glycerin esters of ricinoleic acid (an unsaturated fatty acid). It is rarely, if ever, associated with irritation of the skin or allergic reactions. It is obtained through cold-pressing from seeds or beans of the Ricinus communis (castor oil) plant. Impure castor oil may cause irritation, as the seeds contain a toxic substance that is eliminated during processing. Its unpleasant odor makes it difficult to use in cosmetics.

Uses PEG-30 castor oil, -30 castor oil (hydrogenated), -40 castor oil, -40 castor oil (hydrogenated) are emollients, detergents, emulsifiers, and oil-in-water solubilizers recommended for fragrance oils, and for other oils that may be difficult to solubilize. The -40 castor oil version is a powerful solubilizer for solubilizing essential oils and perfumes in oil-in-water creams and lotions. It is similar to Peg-30 castor oil but denser, being a soft paste rather than a liquid. The hydrogenated version is particularly used as a nonionic emulsifier for essential oils and perfumes.

Production Methods Castor oil is the fixed oil obtained by cold-expression of the seeds of Ricinus communis Linne (Fam. Euphorbiaceae). No other substances are added to the oil.

Definition castor oil: A pale-coloured oil extractedfrom the castor-oil plant. Itcontains a mixture of glyceridesof fatty acids, the predominantacid being ricinoleic acid,C17H32(OH)COOH. It is used as adrying oil in paints and varnishesand medically as a laxative.

Indications Castor oil is a bland oil that is hydrolyzed in the gut to yield ricinoleic acid, the active purging agent. This hydrolysis requires bile, a fact that is sometimes overlooked when castor oil is given as a laxative before radiography in biliary obstruction.The ricinoleic acid acts on the ileum and colon to induce an increased fluid secretion and colonic contraction.

Essential oil composition The oil is a mixture of triglycerides of which 75 to 90% is ricinoleic acid.* This mixture is hydrolyzed to release ricinoleic acid, which exerts a cathartic effect. The cake remaining after the extraction of the oil is the castor pomace. The phytotoxins ricin and ricinine are found in the seed cake and oil. Ricin is a glycoproptein containing neutral A chain and acidic B chain connected by disulfur bonds.

General Description Pale-yellow or almost colorless transparent viscous liquid with a faint mild odor and nauseating taste. Density 0.95 g / cm3. A mixture of glycerides, chiefly ricinolein (the glyceride of ricinoleic acid) .

Air & Water Reactions Insoluble in water.

Reactivity Profile Castor oil can develop heat spontaneously in the air. [Hawley]. Reacts with acids to liberate heat along with alcohols and acids. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides.

Hazard Undergoes spontaneous heating.

Health Hazard If ingested causes severe diarrhea.

Fire Hazard Castor oil is combustible.

Pharmaceutical Applications Castor oil is widely used in cosmetics, food products, and pharmaceutical formulations. In pharmaceutical formulations, castor oil is most commonly used in topical creams and ointments at concentrations of 5–12.5%. However, it is also used in oral tablet and capsule formulations, ophthalmic emulsions, and as a solvent in intramuscular injections.

Therapeutically, castor oil has been administered orally for its laxative action, but such use is now obsolete.

Clinical Use Castor oil is a bland oil that is hydrolyzed in the gut to yield ricinoleic acid, the active purging agent. This hydrolysis requires bile, a fact that is sometimes overlooked when castor oil is given as a laxative before radiography in biliary obstruction.

Safety Profile An allergen. A human skin and eye irritant. Combustible when exposed to heat. Spontaneous heating may occur. To fight fire, use CO2, dry chemical, fog, mist. See also CASTOR BEAN.

Safety Castor oil is used in cosmetics and foods and orally, parenterally, and topically in pharmaceutical formulations. It is generally regarded as a relatively nontoxic and nonirritant material when used as an excipient.

Castor oil has been used therapeutically as a laxative and oral administration of large quantities may cause nausea, vomiting, colic, and severe purgation. It should not be given when intestinal obstruction is present.

Although widely used in topical preparations, including ophthalmic formulations, castor oil has been associated with some reports of allergic contact dermatitis, mainly to cosmetics such as lipsticks.

storage Castor oil is stable and does not turn rancid unless subjected to excessive heat. On heating at 3008℃ for several hours, castor oil polymerizes and becomes soluble in mineral oil. When cooled to 08℃, it becomes more viscous.

Castor oil should be stored at a temperature not exceeding 258℃ in well-filled airtight containers protected from light.

Incompatibilities Castor oil is incompatible with strong oxidizing agents.

Regulatory Status GRAS listed. Included in the FDA Inactive Ingredients Database (IM injections; ophthalmic emulsions; oral capsules and tablets; topical creams, emulsions, ointments, and solutions). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Castor oil Preparation Products And Raw materials

Preparation Products PAINT-->Sebacic acid-->Undecenoic acid-->pesticide emulsifier 56 type-->Amino resin paint-->Sulfonated castor oil-->Heptaldehyde-->Span 80-->Various color nitrocellulose exterior enamel Q04-2-->DL-2-Octanol-->Cremophor EL-->Amylcinnamaldehyde-->GOLD-->ETHYL 10(METHYLSULFONYL)DECANOATE-->12-HYDROXYSTEARIC ACID-->synthetic fiber oil QDH-101-->Cutting liquor,synthetic-->gamma-Decalactone-->pesticide emulsifier PP2-->10-Hydroxydecanoic acid-->ETHYL 10-BROMODECANOATE-->10-METHYLSULFONYL)CAPRIC ACID-->Dibutyl sebacate-->Dicapryl Phthalate-->Compound wax-->10-(METHYLSULFONYL)CAPRAMIDE-->Sulfonated oil DAH-->2-Octanol-->tou-ming oil-->cationic fatliquor agent Z-2-->castor oil polyoxyethylene (90) ether-->PALM FATTY ACID-->11-Oxahexadecan-16-olide-->12-HYDROXYSTEARIC ACID-->Pigment paste-->2-Octanone-->castor oil poloxyethylene (30) ether-->polyoxyethylene (10) castor oil ether-->sodium hydrogen (R)-12-(sulphonatooxy)oleate

 

 

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.

 

Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

 

Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.

 

At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.