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Home > Products >  D-Glucosamine hydrochloride

D-Glucosamine hydrochloride CAS NO.66-84-2

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  • Min.Order: 1 Kilogram
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    99(0-25)Kilogram99(1-1000)Kilogram

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Keywords

  • D-Glucosamine hydrochloride
  • 66-84-2
  • USD$1/KG,IN STOCK

Quick Details

  • ProName: D-Glucosamine hydrochloride
  • CasNo: 66-84-2
  • Molecular Formula: C6H14ClNO5
  • Appearance: powder
  • Application: chemical
  • DeliveryTime: Within 3 days after payment
  • PackAge: foil aluminium bag/vacuum packing
  • Port: Shanghai
  • ProductionCapacity: 100 Kilogram/Day
  • Purity: 85.0-99.8%
  • Storage: keep in dry and cool condition
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram

Superiority

Product Name: D-Glucosamine hydrochloride
Synonyms: 2-DESOXY-2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOPYRANOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOSE HCL;2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDE;D-(+)-GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D(+)-GLUCOSAMINE HYDROCHLORIDE
CAS: 66-84-2
MF: C6H14ClNO5
MW: 215.63
EINECS: 200-638-1
Product Categories: Food & Flavor Additives;Amines;Carbohydrates & Derivatives;Biological and chemical;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Anilines, Aromatic Amines and Nitro Compounds;Aminosugars;Biochemistry;Glucose;Sugars;-;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Other APIs;Food additives;Inhibitors
Mol File: 66-84-2.mol
D-Glucosamine hydrochloride Structure
D-Glucosamine hydrochloride Chemical Properties
Melting point 190-194 °C (dec.)(lit.)
alpha 72.5 º (c=2, H2O, 5hrs.)
refractive index 72 ° (C=1, H2O)
storage temp. Store at RT.
solubility H2O: 0.1 g/mL, clear, colorless
form crystalline
Water Solubility soluble
Merck 14,4458
BRN 4157370
Stability: Stable. Incompatible with strong oxidizing agents. Combustible.
InChIKey QKPLRMLTKYXDST-LPRXMDNASA-N
CAS DataBase Reference 66-84-2(CAS DataBase Reference)
EPA Substance Registry System D-Glucose, 2-amino-2-deoxy-, hydrochloride(66-84-2)
Safety Information
Hazard Codes F,Xi,Xn
Risk Statements 21-36/38-46-62-63
Safety Statements 24/25-53-36/37-26-25
WGK Germany 2
RTECS LZ6665000
F 3-10
Hazard Note Highly Flammable
TSCA Yes
HS Code 29329985
Hazardous Substances Data 66-84-2(Hazardous Substances Data)
MSDS Information
Provider Language
2-Amino-2-deoxy-D-glucopyranose hydrochloride English
SigmaAldrich English
ACROS English
D-Glucosamine hydrochloride Usage And Synthesis
Chemical Properties white powder
Uses Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.
Uses glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties.
Purification Methods Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give  anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]

 

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Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.
 
At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.
 
Henan Coreychem co., LTD. is committed to provide cost effective chemical service to the global fine chemical industry product development agencies; we adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.

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