China (Mainland)
Linoleic acid CAS NO.60-33-3
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- Min.Order: 1 Kilogram
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- Available Specifications:
99(0-25)Kilogram99(1-1000)Kilogram
- Product Details
Keywords
- Linoleic acid
- 60-33-3
- High Cost-Effective
Quick Details
- ProName: Linoleic acid
- CasNo: 60-33-3
- Molecular Formula: C18H32O2
- Appearance: powder
- Application: chemical/high quality
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Day
- Purity: ask
- Storage: keep in dry and cool condition
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
Product Name: Linoleic acid
Synonyms: 9,12-octadecadienoic;LINOLEIC ACID FREE ACID CELL CULTURE*TES TED;ETHYL VINYL KETONE 95+%;LINOLEIC ACID, STANDARD FOR GC;LINOLEIC ACID FREE ACID APPROX. 60%;LINOLEIC ACID FREE ACID, >=99%;LINOLEIC ACID, NATURAL;Linoleic acid, pract.
CAS: 60-33-3
MF: C18H32O2
MW: 280.45
EINECS: 200-470-9
Product Categories: Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives;Antioxidant;Biochemistry;Higher Fatty Acids & Higher Alcohols;Unsaturated Higher Fatty Acids;Natural Plant Extract;-;Biological and chemical;Cell Culture;Lipids and Lipid Carriers;Reagents and Supplements
Mol File: 60-33-3.mol
Linoleic acid Structure
Linoleic acid Chemical Properties
Melting point -5 °C
Boiling point 229-230 °C16 mm Hg(lit.)
density 0.902 g/mL at 25 °C(lit.)
refractive index n20/D 1.466(lit.)
FEMA 3380 | 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
Fp >230 °F
storage temp. 2-8°C
solubility NaOH: soluble1M
pka 4.77(at 25℃)
form liquid
color Clear yellow
Water Solubility INSOLUBLE
FreezingPoint -5℃
Sensitive Air Sensitive
λmax 270nm(H2O)(lit.)
JECFA Number 332
Merck 14,5505
BRN 1727101
Stability: Stability Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey OYHQOLUKZRVURQ-KQHSAVHASA-N
CAS DataBase Reference 60-33-3(CAS DataBase Reference)
NIST Chemistry Reference 9,12-Octadecadienoic acid (Z,Z)-(60-33-3)
EPA Substance Registry System 9,12-Octadecadienoic acid (9Z,12Z)-(60-33-3)
Safety Information
Hazard Codes Xi
Risk Statements 36-36/37/38
Safety Statements 26-24/25-36-37/39
RIDADR UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 1
RTECS RF9990000
F 8-10-23
TSCA Yes
HS Code 29161500
Hazardous Substances Data 60-33-3(Hazardous Substances Data)
MSDS Information
Provider Language
cis-9,cis-12-Octadecadienoic acid English
SigmaAldrich English
ACROS English
ALFA English
Linoleic acid Usage And Synthesis
Linoleic acid and its function Linoleic acid is unsaturated omega-6 fatty acid usually found in corn, safflower, and sunflower oils. As it cannot be synthesized in vivo and has a defined metabolic significance, Linoleic acid is accepted as an essentical nutrient. Linolenic acid gives rise to arachidonic acid, which is the major precursor of a series of bioactive metabolites called eicosanoids, which regulate physiological processes in large scale such as prostaglandins, thromboxane A2, prostacyclin I2, leukotriene B4 and anandamide providing the body anti-inflammatory, moisturizing and healing support.
In 1930, Scientist reported that the rats exhibited scaly skin lesions, impaired growth, tail necrosis, and renal degeneration by the lack of linoleic acid, and the return of this fatty acid to the animal’s diet cured the lesions. Administration of only 1 to 2% of dietary calories in the form of linoleic acid will support normal growth and development and prevent the clinical appearance of essential fatty acid deficiency (EFAD). Linoleic acid deficiency possibly happens in infants fed skimmed milk, in patients with chronic fat malabsorption, and in those undergoing total parenteral nutrition, which will cause poor growth and development in infants and dermatitis in adults.
Brief Introduction Linoleic acid is named cis-9, 12-octadecadienoic acid, can also use △ to denote double bond, thus being named △ 9, 12-octadecadienoic acid. Alternatively, it can be simply expressed as 9C, 12C-18: 2 or C18: 2.
Linoleic acid in foods is important for human body to maintain many physiological functions such as the synthesis of phospholipids and other lipid metabolism, etc., being capable f significantly lower the effect of serum cholesterol. It can correct the growth arrest, skin and hair abnormalities, abnormal serum and adipose tissue composition of experimental animals due to lack of essential fatty acids. Lack of it in human beings can affect cell membrane function. Lack in infants can cause eczema. It is currently the major unsaturated fatty acids used to prevent and treat hyperlipidemia. Plant fat is the main source of linoleic acid, of which soybean oil, corn oil and cottonseed oil content is particularly rich. The content in vegetable oil (except palm oil), fish fat and poultry fat is also high. It is generally recommended that the amount of dietary linoleic acid should be equivalent to more than 2% to 3% of the total dietary calories.
Pharmaceutical effects Linolenic acid is the unsaturated acids obtained from the extraction and vacuum distillation of the saponification product of soybean oil. It contains over 65% of pure linoleic acid as well as vitamin E being as an antioxidant. Linoleic acid can react with cholesterol to become esters, which is more easily transported, metabolized and excreted, thus reducing blood cholesterol levels. It can also reduce the triglycerides content in the blood. Unsaturated fatty acids may change the distribution of cholesterol in the body, making it deposited in the tissue outside the vessel wall, further reducing the cholesterol content of the vessel wall for preventing and treating atherosclerosis.
Details
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.
At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.
Henan Coreychem co., LTD. is committed to provide cost effective chemical service to the global fine chemical industry product development agencies; we adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.