China (Mainland)
6-aminocaproic Acid CAS NO.60-32-2
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- Min.Order: 2 Kilogram
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- Available Specifications:
98(0-25)Kilogram98(1-100)Kilogram
- Product Details
Keywords
- 6-aminocaproic Acid
- 60-32-2
- High Cost-Effective
Quick Details
- ProName: 6-aminocaproic Acid
- CasNo: 60-32-2
- Molecular Formula: C6H13NO2
- Appearance: ask
- Application: intermediates
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: shanghai
- ProductionCapacity: 150 Kilogram/Week
- Purity: 85.0-99.8%
- Storage: Keep in dry and cool condition
- Transportation: by air or by sea
- LimitNum: 2 Kilogram
- Melting Point: 204-209oC
- Boiling Point: 255.6oC at 760 mmHg
- Water Solubility: SOLUBLE
- Density: 1.042 g/cm3
- Storage Temp: 2-8oC
- Flash Point: 108.4oC
- Appearance: white crystalline powder
- RTECS: MO6300000
- Safety Statements: S26-S36
- HS Code: 29224995
Superiority
Product Name: 6-Aminocaproic acid
Synonyms: 6-Aminohexanoic acid 60-32-2;Pyrogallol ;6-Aminocaproic acid 60-32-2 6-Aminohexanoic acid;177 J.D;177 J.D.;177j.d.;177jd;6-amino-hexanoicaci
CAS: 60-32-2
MF: C6H13NO2
MW: 131.17
EINECS: 200-469-3
Product Categories: -;AMICAR;Pharmaceutical raw materials;Amino Acids;Organic acids;omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Fibrinogen/Thrombin
Mol File: 60-32-2.mol
6-Aminocaproic acid Structure
6-Aminocaproic acid Chemical Properties
Melting point 207-209 °C (dec.)(lit.)
Boiling point 242.49°C (rough estimate)
density 1.03 g/mL at 20 °C
vapor pressure <0.1 hPa (20 °C)
refractive index 1.4870 (estimate)
Fp 207-209°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
pka 4.373(at 25℃)
color white
PH 7.0-7.5 (50g/l, H2O, 20℃)
Water Solubility SOLUBLE
Merck 14,432
BRN 906872
InChIKey SLXKOJJOQWFEFD-UHFFFAOYSA-N
CAS DataBase Reference 60-32-2(CAS DataBase Reference)
NIST Chemistry Reference Hexanoic acid, 6-amino-(60-32-2)
EPA Substance Registry System Hexanoic acid, 6-amino-(60-32-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS MO6300000
TSCA Yes
HS Code 29224995
Hazardous Substances Data 60-32-2(Hazardous Substances Data)
Toxicity LD50 in rats (g/kg): 7.0 i.p.; ~3.3 i.v. (Hallesy)
MSDS Information
Provider Language
6-Aminohexanoic acid English
SigmaAldrich English
ACROS English
ALFA English
6-Aminocaproic acid Usage And Synthesis
Description 6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
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Chemical Properties white crystalline powder
Uses hemostatic
Uses 6-Aminohexanoic Acid is a reagent commonly used for the extraction of aldehydes from reaction mixtures. 6-Aminohexanoic Acid has also been shown to improve solubilization of membrane proteins in elect rophoresis. Studies suggest that 6-Aminohexanoic Acid inhibits the activation of the first component of the complement system.
Uses Propylparaben Food preservative
Uses EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
Definition ChEBI: An amino-acid anion that is the conjugate base of 6-aminohexanoic acid.
Brand name Amicar (Xanodyne).
Safety Profile Moderately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.
Veterinary Drugs and Treatments Aminocaproic acid has been used as a treatment to degenerative myelopathy (seen primarily in German shepherds), but no controlled studies documenting its efficacy were located. There is interest in evaluating aminocaproic acid for adjunctive treatment of thrombocytopenia in dogs, but efficacy and safety for this purpose remains to be investigated. In humans, it is primarily used for treating hyperfibrinolysis-induced hemorrhage.
Details
WGK Germany:2
Risk Statements:R36/37/38
Hazard Codes:Xi:Irritant
CAS No.:60-32-2
Synonyms:View MoreAminocaproic acid; 4-aminobutyltrimethoxysilane; 6-amino-n-hexanoic acid; 6-amino-n-caproic acid; aminobutyltrimethoxysilane; 6-amino-hexanoic acid;
Formula:C6H13NO2
Exact Mass:131.09500
Molecular Weight:131.17300
PSA:63.32000
LogP:1.29040
| 6-aminocaproic Acid | |
| CAS No.: | 60-32-2 |
|---|---|
| Synonyms: | |
| Formula: | C6H13NO2 |
| Exact Mass: | 131.09500 |
| Molecular Weight: | 131.17300 |
| PSA: | 63.32000 |
| LogP: | 1.29040 |
|
Properties
|
|
| Melting Point: | 204-209oC |
|---|---|
| Boiling Point: | 255.6oC at 760 mmHg |
| Water Solubility: | SOLUBLE |
| Density: | 1.042 g/cm3 |
| Storage Temp: | 2-8oC |
| Flash Point: | 108.4oC |
| Appearance: | white crystalline powder |
|
Safety Info
|
|
| RTECS: | MO6300000 |
|---|---|
| Safety Statements: | S26-S36 |
| HS Code: | 29224995 |
| WGK Germany: | 2 |
| Risk Statements: | R36/37/38 |
| Hazard Codes: | Xi:Irritant |
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