Carbohydrazide CAS NO.497-18-7

Product Name: Carbohydrazide

Synonyms: 1,3-Diaminomocovina;1,3-diamino-ure;4-amino-semicarbazid;Cabazide;1,3-DIAMINOUREA;Carbohydrazide58%;CARBOHYDRZIDE;CHZ Oxygen Scavenger

CAS: 497-18-7

MF: CH6N4O

MW: 90.08

EINECS: 207-837-2

Product Categories: Pharmaceutical Intermediates;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;API intermediates;Water Ttreatment Chemicals;Carbonyl Compounds;Hydrazides;-;Organic Building Blocks;Chemical raw materials;API;boiler water treatment of deoxidizer;Fine Chemical;corrosion inhibitor

Mol File: 497-18-7.mol

Carbohydrazide Structure

Carbohydrazide Chemical Properties

Melting point 150-153 °C(lit.)

Boiling point 167.26°C (rough estimate)

density 1.02

refractive index 1.4164 (estimate)

storage temp. 0-6°C

form Crystalline Powder

color White

Water Solubility Soluble in water.

Merck 14,1804

BRN 1747069

Stability: Stable, but may explode if heated. Incompatible with strong acids, strong oxidizing agents.

InChIKey XEVRDFDBXJMZFG-UHFFFAOYSA-N

CAS DataBase Reference 497-18-7(CAS DataBase Reference)

NIST Chemistry Reference Carbonic dihydrazide(497-18-7)

EPA Substance Registry System Carbonic dihydrazide(497-18-7)

Safety Information

Hazard Codes Xi,N,Xn

Risk Statements 5-22-51/53-36/37/38-20/21/22-43-38

Safety Statements 61-36/37/39-36/37

RIDADR UN3077

WGK Germany 3

RTECS FF2625000

TSCA Yes

HazardClass 9

PackingGroup III

HS Code 29280000

MSDS Information

Provider Language

1,3-Diaminourea English

ACROS English

SigmaAldrich English

ALFA English

Carbohydrazide Usage And Synthesis

Product Features Carbohydrazide is a white crystalline thin and short columnar crystal or white powder at room temperature. It is insoluble in alcohol, easily soluble in water with dissolution absorbing heat. It is insoluble in alcohol, ether, and benzene. Owing to that, it is a kind of derivative of hydrazine and thus having strong reduction ability. It is non-toxic, and can replace hydrazine and oximes. It has a broad range of application in industry. For example, it can be used as the oxygen scavenging agent of boiler water in the field of water treatment and is regarded as most advanced materials for oxygen scavenging of boiler water. It has a low toxicity and high melting point with its deoxidizing efficiency being far greater than the current materials used and is a idea product for both safety and environmental protection; it can also be used as a rocket propellant components; moreover, owing to that its hydrogen atoms attached to the nitrogen atom is easily substituted by other groups, it can be used as the cross-linking agents of elastic fibers in the textile field, the formaldehyde scavenger, as well as the antioxidant of carotene pigment. In addition, adding an appropriate amount of carbohydrazide to the phenol fungicides containing can play a role on preventing discoloration and rancidity. As a chemical raw material and chemical industry intermediates, it is widely used in medicine, herbicides, plant growth regulators, dyes and other industries.

Oxygen scavenger of the boiler water When acting as the oxygen scavenger of boiler water, carbohydrazide may be directly added into the water while its aqueous solution can also be used. The usage amount of carbohydrazide for scavenging 1mol O2 is 0.5mol, and should be appropriately in excess. The proper temperature range is 87.8-176.7 ℃. The optimal time for applying carbohydrazide is after the thermal scavenging of oxygen. The reaction of oxygen and carbohydrazide is as follows: CON4H6 + 2O2 = 2N2 + 3H2O + CO2

Reference quality standards Item Index 

Appearance: fine white crystals or white short columnar crystals

Purity% ≥98.0%

Free hydrazine ≤250.0mg/L

Loss of weight by drying ≤0.2%

PH (12% aqueous solution) 8.45 ± 1.25

Uses It is widely used in the production of pharmaceuticals, herbicides, plant growth regulators, dyes, etc.(1) carbohydrazide is a derivative of hydrazine with a strong reduction. It can be not only used as the intermediates for producing energy-containing materials, but also can be used directly as the components of explosives and propellants. (2) it can be used as the preservative of refinery equipment and can also be used as the oxygen scavenger of boiler water treatment agent (3) It can be used as the cross-linking agent of the elastic fiber in the field of chemical fiber industry (4) it can be used as the chemical raw materials and chemical industrial intermediates and is widely used in medicine, herbicides, plant growth regulators, dyes and other industries. 

It can be used as the component of the rocket propellant, the stabilizer of color development and soap quality, the antioxidants of rubber, the oxygen scavenger of boiler water, and the passivation agent of metal. 

Carbohydrazide is a derivative of hydrazine with a strong reduction. It can be used as the intermediate of producing energy-containing materials and also be used directly for the components of explosives and rocket propellant. It can also be used as the oxygen scavenger of boiler water and is the most advanced materials for scavenging oxygen of boiler water in the world today. It has low toxicity, high melting point and a deoxidation efficiency being far greater than the materials currently used. It is an ideal product for both safety and environmental protection. In addition, it can be used as the cross-linking agent of the elastic fiber in the field of chemical fiber industry. It can also be used as the chemical raw materials and chemical industrial intermediates and is widely used in medicine, herbicides, plant growth regulators, dyes and other industries.

The above information is edited by the chemicalbook of Dai Xiongfeng.

Category toxic substances

Toxicity grading poisoning

Acute toxicity Intraperitoneal-mouse LD50: 167 mg/kg; Intravenous-Mouse LD50: 120 mg/kg.

Explosive and hazardous characteristics it is explosive upon heating; it can generate explosive diazide compound upon reaction with nitrous acid.

Flammability and hazard characteristics thermal decomposition into toxic nitric oxide gas.

Storage characteristics Treasury: ventilation, low-temperature and drying; it should be stored separately from strong acids and strong oxidants.

Extinguishing agent Water, carbon dioxide, dry powder, foam.

Chemical Properties white powder

Uses Organic intermediate and photographic chemical.

Definition ChEBI: A carbohydrazide obtained by formal condensation between hydrazinecarboxylic acid and hydrazine.

Safety Profile Poison by intravenous and intraperitoneal routes. Reacts with nitrous acid to form the explosive carbonic dazide. When heated to decomposition it emits toxic fumes of NOx.

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.

 

Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

 

Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.

 

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