China (Mainland)
Doramectin CAS NO.117704-25-3
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,Other
- Available Specifications:
98(0-25)Metric Ton98(1-100)Metric Ton
- Product Details
Keywords
- Coreychem Important product
- Advanced and completed testing facilities
- High Cost-Effective
Quick Details
- ProName: Doramectin
- CasNo: 117704-25-3
- Molecular Formula: C50H74O14
- Appearance: ask
- Application: intermediates
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: Shanghai
- ProductionCapacity: 120 Kilogram/Week
- Purity: 85.0-99.8%
- Storage: Keep in dry and cool condition
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- Melting Point: 116 - 119oC
- Boiling Point: 967.4oC at 760 mmHg
- Density: 1.25 g/cm3
- Storage Temp: 0-6oC
- Appearance: white to off-white crystalline powder
- Vapor Pressure: 0mmHg at 25°C
- Refractive Index: 1.579
- Safety Statements: 33-45-60-61-36/37-26
- Risk Statements: R25
- CAS No.: 117704-25-3
Superiority
| Product Name: | Doramectin |
| Synonyms: | 25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN;DORAMECTIN;Doramectin VETRANAL;Doromectin; 25-Cclohexyl-avermectin B1;25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1A;Dectoma;UK-67994 |
| CAS: | 117704-25-3 |
| MF: | C50H74O14 |
| MW: | 899.11 |
| EINECS: | 601-490-4 |
| Product Categories: | -;Antiparasitic;Intermediates & Fine Chemicals;Pharmaceuticals;IMIPEM;Inhibitors;raw material- |
| Mol File: | 117704-25-3.mol |
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| Doramectin Chemical Properties |
| Melting point | 116-1190C |
| storage temp. | 0-6°C |
| solubility | methanol: soluble |
| form | solid |
| color | white |
| InChIKey | QLFZZSKTJWDQOS-YDBLARSUSA-N |
| Safety Information |
| Hazard Codes | T,N,Xi |
| Risk Statements | 25-50/53-36/37/38 |
| Safety Statements | 33-45-60-61-36/37-26 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29419090 |
| Hazardous Substances Data | 117704-25-3(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| Doramectin | English |
| Doramectin Usage And Synthesis |
| Pig antiparasitic |
Doramectin is a new generation of antiparasitic , compared with other commercially available ivermectin products, anti-parasite range of Doramectin is broader, with better effect, and Doramectin can prevent parasite reinfection for a longer valid time, It is the world's best, the most potential anti-parasitic drugs for development veterinary . Doramectin as a pesticide can kill all the the internal and external parasites , and is also valid to nematodes, arthropods. At present, Chinese pig industry commonly used insecticide drugs include: parasite drugs: albendazole, levamisole, trichlorfon, Vietnam, hygromycin, ivermectin, avermectin. External parasite drugs: trichlorfon, amitraz, diazinon, permethrin drugs, avermectin, ivermectin. Doramectin has a good effect on pig gastrointestinal nematodes , it is reported that pig is injected 0.3 mg/kg by intramuscular, dosing artificial and natural infection cases after 7 days , 14 days, 21 days, weight gains is significantly higher (swine P <0.0001); compared with the control group, percentage of getting rid of worms is 100%, and there are no side effects. In Pig scabies mite treatment, from piglets to sows ,Doramectin has good results .After artificial infection scabies mites, according to the body weight ,administrated 0.3 mg/kg intramuscularly, four weeks after the test, the result of inflammation of the skin injury in pigs and worms Elimination of infected body, is very significant (P <0.05). Treatment for pregnant sows kidney worm, press the 0.3 mg/kg dose neck single injection, the 56 day and 57 day of testing, the detection rate of Urine eggs is 0, the percentage of getting rid of them is 100%, while the control group per milliliter of urine displays 3762 eggs. For lung worms, lice and other pigs parasites,it has the same effect. According to more than l ng/g tissue concentration of the drug having anti-parasitic activity, the drug can be used to assess the validity. Duration time of Ivermectin is greater than 1 ng/g concentration :18 days for the skin, the lungs 18 days, 18 days for gastrointestinal mucosa, gastric mucosa wrinkled 18 days. Duration time of Doramectin is greater than 1 ng/g concentration: 26 days for the skin, the lungs 38 days, 38 days for gastrointestinal mucosa, gastric mucosa wrinkled 38 days. Thus,duration time of more than 1 ng/g doramectin in the gastrointestinal mucosa, lung tissue is 38 days, 20 days more than ivermectin. So the effect of doramectin to drive and to kill the parasites is stronger than ivermectin, and it can be effective to prevent the parasite reinfection . The above information is edited by the Chemicalbook of Tian Ye. |
Details
Synonyms:View Moredoramectine; Dectoma; DONGGUAI.P.E; Doramecin; Doramectina; Dectomax; Doromectin; 25-cyclohexyl-avermectin B1;
Formula:C50H74O14
Exact Mass:898.50800
Molecular Weight:899.11400
PSA:170.06000
LogP:5.91160
| Doramectin | |
| CAS No.: | 117704-25-3 |
|---|---|
| Synonyms: |
View More
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| Formula: | C50H74O14 |
| Exact Mass: | 898.50800 |
| Molecular Weight: | 899.11400 |
| PSA: | 170.06000 |
| LogP: | 5.91160 |
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Properties
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| Melting Point: | 116 - 119oC |
|---|---|
| Boiling Point: | 967.4oC at 760 mmHg |
| Density: | 1.25 g/cm3 |
| Storage Temp: | 0-6oC |
| Appearance: | white to off-white crystalline powder |
| Vapor Pressure: | 0mmHg at 25C |
| Refractive Index: | 1.579 |
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Safety Info
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| Safety Statements: | 33-45-60-61-36/37-26 |
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| Risk Statements: | R25 |
Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates fine chemicals custom synthesis, scale-up production and rare chemicals trade. We have experienced research staff, strong technical force, well-equipped machine, and considerate marketing team service, with a strict customer intellectual property security system, we are already become good partner of customers from difficult and complex chemical and biological chemical field. Our high quality & low price and effective services shortened new product development cycle,reduced the development and production cost for numerous partners.
The company has completed numerous domestic and overseas famous pharmaceutical, chemical, biological and other large and medium-sized company R&D outsourcing services, synthesis process development and optimization services, chemical intermediates customized service, special chemical processing and production services, etc., We hope to become continuous mutually beneficial partnership with you, to create a better business opportunities together.
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1. Samples synthetic, Our strong r&d team has accumulated abundant experience in synthesis design and exploring synthesis of new technology. Not only good at heterocyclic chemistry, chiral chemicals (asymmetric synthesis and enzyme reaction), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry including nucleosides, nucleotides, sugar chemical, peptide chemistry, etc, to complete the synthesis from mg to kg samples in lab scale. Our efficient management and good communication skills and ability to solve the problem rapidly in order to ensure quality, timely delivery, based on the standard client confidential system and competitive price products,we has been recognized and praised by many customers in chemical industry.
2. Scale-up production, based on our rich laboratory experience and advanced equipment in production base, also depend on accumulation of advantages in many aspects as industrialized technology development, the production cost control, to provide from kg class to wt class custom synthesis scale-up production services to the global fine chemical industry, can be carried out oxidation, hydrogenation pressure (70 kg), halide, and acylation, esterification, condensation, cyclization, formatting, ammoniation, diazotization and azide reaction, our experienced production management, strict and perfect management system can quickly provide customers with competitive and fine mass production services.
3.Technology transfer, the company has accumulated a large number of production processes of drugs, intermediates and raw material. Based on the principle of mutual benefit, and some technology transfer to industry manufacturers, also provides them marketing support.
4. Purchasing agency service, Our excellence professional sales team, timely and thoughtful service, in addition to the necessary good language communication ability of professional sales staff, also equipped with professional chemical technical sales consultant, who can answer the customer's academic professional question, we are in line with the aim of offering customer wholehearted service, with our advanced testing equipment checks and abundant R&D and production of domestic partner contacts, to provide rare chemicals with standard purity, reasonable price and cost-effective purchasing agency service to foreign customers, and the help you shorten the sourcing time, reduce the purchasing cost.