Dibutyl sebacate competitive product CAS NO.109-43-3
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- Min.Order: 1 Kilogram
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Quick Details
- ProName: Dibutyl sebacate competitive product
- CasNo: 109-43-3
- Molecular Formula: C18H34O4
- Appearance: according to email quotation
- Application: pharmaceutical raw materials
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Week
- Purity: 99%
- Storage: Keep in dry and cool condition
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- CAS No.: 109-43-3
- Synonyms: Dibutyl sebacinate
- Formula: C18H34O4
- Molecular Weight: 314.46
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Coreychem focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals trade.Product category including Intermediates&API,Catalyst and Electronic Chemicals.Covering 811 square meters R&D center,with 45 person R&D team,our synthesis level is well-known to the industry,which are exported to France,Poland,Czech,Ukraine,Spain,Switzerland,etc...
Details
Product Name: | Dibutyl sebacate |
Synonyms: | Dibutyl sebacinate;dibutyl1,8-octanedicarboxylate;Dibutylester kyseliny sebakove;dibutylesterkyselinysebakove;Kodaflex DBS;kodaflexdbs;Monoplex dbs;monoplexdbs |
CAS: | 109-43-3 |
MF: | C18H34O4 |
MW: | 314.46 |
EINECS: | 207-395-0 |
Product Categories: | pharmacetical;Piperazine derivates;Fatty Acid Esters (Plasticizer);Functional Materials;Plasticizer |
Mol File: | 109-43-3.mol |
|
Dibutyl sebacate Chemical Properties |
Melting point | 205 °C (dec.)(lit.) |
Boiling point | 178-179 °C3 mm Hg(lit.) |
density | 0.94 |
refractive index |
n |
FEMA | 2373 | DIBUTYL SEBACATE |
Fp | >230 °F |
solubility | hexane, toluene, ethanol and acetone: soluble |
form | Liquid |
Specific Gravity | 0.937 (20/4℃) |
color | Clear |
JECFA Number | 625 |
BRN | 1798308 |
CAS DataBase Reference | 109-43-3(CAS DataBase Reference) |
NIST Chemistry Reference | Di-n-butyl sebacate(109-43-3) |
EPA Substance Registry System | Decanedioic acid, dibutyl ester(109-43-3) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 40-36/37/38 |
Safety Statements | 36/37-36-26 |
WGK Germany | 3 |
RTECS | VS1150000 |
TSCA | Yes |
HS Code | 29171390 |
Hazardous Substances Data | 109-43-3(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Dibutyl sebacate | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
Dibutyl sebacate Usage And Synthesis |
Chemical Properties | clear liquid |
Chemical Properties | Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor. |
Uses | Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant. |
Production Methods | Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid. |
Preparation | By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride |
Pharmaceutical Applications |
Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations. Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages. |
Safety Profile | Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL. |
Safety |
Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate. LD50 (rat, oral): 16g/kg |
storage | Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions. |
Incompatibilities | Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis. |
Regulatory Status | Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients. |