2-Methylbenzene-1-sulfonamide competitive product CAS NO.88-19-7
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Quick Details
- ProName: 2-Methylbenzene-1-sulfonamide compet...
- CasNo: 88-19-7
- Molecular Formula: C7H9NO2S
- Appearance: according to email quotation
- Application: pharmaceutical raw materials
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: Shanghai
- ProductionCapacity: 100 Kilogram/Week
- Purity: 99%
- Storage: Keep in dry and cool condition
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- CAS No.: 88-19-7
- Synonyms: -methylbenzenesulphonamide;
- Formula: C7H9NO2S
- Molecular Weight: 171.22
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Details
Product Name: | 2-Methylbenzene-1-sulfonamide |
Synonyms: | o-methylbenzenesulphonamide;ortho-Toluenesulfonamide;Ortho-toluol-sulfonamid;o-toluenesulphonamide;O-Toluenseslfonamide;toluene-2-sulphonamide;Uniplex 171;o-Methylbenzenesulfonamide |
CAS: | 88-19-7 |
MF: | C7H9NO2S |
MW: | 171.22 |
EINECS: | 201-808-8 |
Product Categories: | SULFONAMIDE;Intermediates;Organics;Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds;Aromatics, Impurities, Mutagenesis Research Chemicals, Sulfur & Selenium Compounds;Pharmaceutical Intermediates |
Mol File: | 88-19-7.mol |
|
2-Methylbenzene-1-sulfonamide Chemical Properties |
Melting point | 155 °C |
Boiling point | 221 °C |
density | 1.2495 (rough estimate) |
refractive index | 1.6100 (estimate) |
Fp | 178°C |
form | neat |
Water Solubility | Soluble in water (1.6 g/L at 25°C). |
BRN | 1102362 |
InChIKey | YCMLQMDWSXFTIF-UHFFFAOYSA-N |
CAS DataBase Reference | 88-19-7(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenesulfonamide, 2-methyl-(88-19-7) |
EPA Substance Registry System | Benzenesulfonamide, 2-methyl-(88-19-7) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36-40 |
Safety Statements | 26-36/37 |
WGK Germany | 1 |
RTECS | XT5075000 |
TSCA | Yes |
HS Code | 29350090 |
Hazardous Substances Data | 88-19-7(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
2-Methylbenzene-1-sulfonamide | English |
SigmaAldrich | English |
ACROS | English |
ALFA | English |
2-Methylbenzene-1-sulfonamide Usage And Synthesis |
Chemical Properties | 2-Methylbenzene-1-sulfonamide is Colorless crystals. Soluble in alcohol; slightly soluble in water and ether. Combustible. |
Uses | 2-Methylbenzene-1-sulfonamide is a methylated sulfonamide and a major Impurity if Saccharin (S080800). Studies suggest that o-Toluenesulfonamide has potential mutagenic activity. |
Uses | Plasticizer of thermosetting resin, as a raw material used in organic synthesis, preparation of nail polish, dyes, fluorescent pigments and coatings. |
Safety Profile | Suspected carcinogen with experimental tumorigenic data. Mildly toxic by ingestion. Experimental reproductive effects. Mutation data reported. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx. Used as a chemical intermediate in the production of saccharin. |
Purification Methods | Crystallise the amide from hot H2O (m 153o), then from EtOH or Et2O/pet ether. The N-o-toluenesulfonylphthalimide has m 182o (from EtOH). [Evans & Dehn J Am Chem Soc 51 3652 1929, Beilstein 11 H 86, 11 I 23, 11 II 39, 11 III 167, 11 IV 229.] |
2-Methylbenzene-1-sulfonamide Preparation Products And Raw materials |
Raw materials | Toluene-->Ammonium hydroxide-->Chlorosulfonic acid-->O-TOLUENESULFONYL CHLORIDE |
Preparation Products | Chlorsulfuron-->Saccharin sodium -->2-CARBOXY PHENYLSULFAMIDE |