Isoflavone CAS NO.574-12-9

Product Name: Isoflavone

Synonyms: Soy Isoflavione;BioaActive Soy Isoflavones;Nanoactive Soy Isoflavones;Soluble Soy Isoflavones;4H-1-Benzopyran-4-one,3-phenyl-;3-Phenylchromen-4-one;3-phenyl-4h-1-benzopyran-4-one;ISOFLAVONE

CAS: 574-12-9

MF: C15H10O2

MW: 222.24

EINECS: 611-522-9

Product Categories: -;Plant extracts;Herb extract

Mol File: 574-12-9.mol

Isoflavone Structure

Isoflavone Chemical Properties

Melting point 148°

Boiling point 323.41°C (rough estimate)

density 1.1404 (rough estimate)

refractive index 1.6600 (estimate)

CAS DataBase Reference 574-12-9(CAS DataBase Reference)

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MSDS Information

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Isoflavone English

Isoflavone Usage And Synthesis

Main effects Isoflavones are non-nutritive botanical compounds that are rich in soy products and a few other plant species; both genistein and  glycetein are isoflavones. Their chemical structure looks similar to estrone (also known as estrogen), a steroid hormone.

 

Plant sources: produced mainly from soybeans, lentils, pod legumes s well as highly processed food made from soybeans such as vegetarian meat, soybean flour, tofu and soy milk. Among them, tofu retains more of isoflavone content than milk.

 

Main functions of isoflavones：

Reduce LDL cholesterol, help to prevent or cure menopausal syndromes and provide the linoleic acid and linoloinic acid needed by human body.

Balance blood cholesterol and reduce blood cholesterol levels.

Make arteries more flexible and prevent damage to heart

Enhance bone density, reduce calcium loss and reduce the chance of suffering from osteoporosis.

Reduce the chance of suffering from cancer, especially breast cancer and prostate cancer.

Relieve menopause discomfort, such as hot flash, fever, emotional instability, headache, insomnia, fatigue, night sweats, vaginal dryness and so on.

Treat Enteritis syndrome, hot flash, osteoporosis, cardiovascular disease and cancer, also help fight coronary heart disease.

Flavonoids can reduce the formation of free radicals and help regeneration of other antioxidants. Soy isoflavones are a type of natural plant estrogen which is good to human body. The plant bioactive element extracted from natural soybeans is very similar to the estrogen molecular structure and can be combined with female estrogen receptors and play two-ways regulation on estrogen safely and with no side effects, so it is also known as "phytoestrogen." It can relieve osteoporosis and other symptoms caused by menopause, delay skin aging, improve skin quality, make female skin smooth, delicate and elastic. Due to its role in improvement of women life quality, it is also called "feminine charm factor".

Isomers of flavonoids Isoflavones are isomers of flavones with some physiological activity.The phenyl group side chain of its γ-pyrazone ring is not connected to C2 position but to C3 position. Natural isoflavones are mainly found in angiosperms and some members of the Fabaceae Rosaceae and Iridaceae family. The kudzu root, one of the legume contains five isoflavone derivatives, namely, glycinin, daidzein, puerarin, puerarin- 7-xyloside and daidzein-4 ', 7-diglucoside. The structure of isoflavones compound are similar to that of estrogen, so generally it is regarded as the precursor substances of hormone, and it differs from flavonoids compound in its negative reaction against hydrochloric acid and magnesium powder.

Uses Antioxygenation, estrogen-like, cancer prevention and anti-cancer, disease prevention such as senile dementia, cardiovascular diseases and breast cancer, improvement of life quality.

Definition ChEBI: A simplest member of the class of isoflavones that is 4H-chromen-4-one in which the hydrogen at position 3 is replaced by a phenyl group.

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.

 

Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

 

Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.

 

At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.

 

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