China (Mainland)
Gallic acid 149-91-7 Manufacturer CAS NO.149-91-7
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms:
- Available Specifications:
Level 1(1-9)Kilogram
- Product Details
Keywords
- 149-91-7
- Gallic acid
- Gallic acid 149-91-7 Price
Quick Details
- ProName: Gallic acid 149-91-7 Manufacturer
- CasNo: 149-91-7
- Molecular Formula: C7H6O5
- Appearance: White crystalline to greyish powder
- Application: Food/Medicine/Industria grade
- DeliveryTime: Within 3 days after payment
- PackAge: foil aluminium bag/vacuum packing
- Port: shanghai
- ProductionCapacity: 3 Kilogram/Day
- Purity: 99%min
- Storage: Keep in dry and cool condition
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- Minimum order quantity: 1
- Company: kilogram
- Supply capacity: 3
- Supply time unit: day
- Time of delivery: Within 3 days after payment
- Packing method: foil aluminium bag/vacuum packing
- Transport conditions: by air or by sea
- Port: shanghai
- Synonyms: Gallic acid; 3,4,5-Trihydroxybenzoic a...
- MF: C7H6O5
- EINECS No: 205-749-9
- Product name: Gallic acid
- MF: (HO)3C6H2COOH
- EINECS: 205-749-9
- MW: 188.13
- Other Names: 3,4,5-Trihydroxybenzoic Acid
Superiority
Career Henan Chemical Co, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates fine chemicals custom synthesis, scale-up production and rare chemicals trade. We have experienced research staff, strong technical force, well-equipped machine, and considerate marketing team service, with a strict customer intellectual property security system, we are already become good partner of customers from difficult and complex chemical and biological chemical field. Our high quality & low price and effective services shortened new product development cycle,reduced the development and production cost for numerous partners.
Details
Scale-up production, based on our rich laboratory experience and advanced equipment in production base, also depend on accumulation of advantages in many aspects as industrialized technology development, the production cost control, to provide from kg class to wt class custom synthesis scale-up production services to the global fine chemical industry, can be carried out oxidation, hydrogenation pressure , halide, and acylation, esterification, condensation, cyclization, formatting, ammoniation, diazotization and azide reaction, our experienced production management, strict and perfect management system can quickly provide customers with competitive and fine mass production services.
| Product Name: | Gallic acid |
| Synonyms: | TIMTEC-BB SBB008781;RARECHEM AL BE 0070;3,4,5-trihydroxy-benzoicaci;gallic;Gallussaure;Kyselina 3,4,5-trihydroxybenzoova;Kyselina gallova;kyselina3,4,5-trihydroxybenzoova |
| CAS: | 149-91-7 |
| MF: | C7H6O5 |
| MW: | 170.12 |
| EINECS: | 205-749-9 |
| Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Fine chemicals;Food additive,Antioxidant anticorrosive;Inhibitors;Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts |
| Mol File: | 149-91-7.mol |
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| Gallic acid Chemical Properties |
| Melting point | 252 °C (dec.)(lit.) |
| Boiling point | 259.73°C (rough estimate) |
| density | 1.694 |
| refractive index | 1.5690 (estimate) |
| storage temp. | Store below +30°C. |
| form | Powder |
| pka | 4.41(at 25℃) |
| color | Off-white |
| Water Solubility | 12 g/L cold water |
| Merck | 14,4345 |
| BRN | 2050274 |
| Stability: | Stability Stable, but may discolour upon exposure to light. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, acid chlorides, acid anhydrides. |
| InChIKey | LNTHITQWFMADLM-UHFFFAOYSA-N |
| CAS DataBase Reference | 149-91-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 3,4,5-trihydroxy-(149-91-7) |
| EPA Substance Registry System | Benzoic acid, 3,4,5-trihydroxy-(149-91-7) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-37/39 |
| WGK Germany | 2 |
| RTECS | LW7525000 |
| F | 8-9-23 |
| TSCA | Yes |
| HS Code | 29182900 |
| Hazardous Substances Data | 149-91-7(Hazardous Substances Data) |
| Toxicity | LD50 in rabbits (g/kg): 5.0 orally (Dollahite) |
| MSDS Information |
| Provider | Language |
|---|---|
| 3,4,5-Trihydroxybenzoic acid | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Gallic acid Usage And Synthesis |
| Chemical Properties | Colorless crystalline needles or prisms obtained from nutgall tannins,gallic acid is soluble in water and alcohol and melts at 235 to 240 °C. Also known as trihydroxybenzoic acid, it is used in photography, tanning, ink manufacture and pharmaceuticals. |
| Uses | antineoplastic, astringent, antibacterial |
| Uses | A cyclooxygease inhibitor substance found in plants. |
| Uses | gallic acid is a potential bleaching agent and anti-oxidant, it is also astringent and potentially anti-microbial and anti-fungal. Scientists are finding that gallic acid may serve as a skin-lightening agent by inhibiting the action of the tyrosinase and peroxidase enzymes. Some studies indicate that it is more effective than hydroquinone when combined with the proper ingredients. It is also incorporated into anti-aging formulations for its ability to prevent mucopolysaccaride deterioration. It is a constituent of witch hazel and oak bark, among many other plants; however, it is generally obtained from nutgalls for commercial purposes. |
| Definition | ChEBI: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5. |
| Uses | Gallic acid is a trihydroxybenzoic acid found in many plants as either the free acid or in the esterified form of gallotannins and ellagitannins. It demonstrates antioxidant activity by scavenging 2,2-diphenyl-1-picrylhydrazyl and hydroxyl free radicals with IC50 values of 9.4 and 191 μM, respectively, and inhibiting microsomal lipid peroxidation with an IC50 value of 1.51 μM. Gallic acid is often used as a standard for determining the phenol content of various analytes by the Folin-Ciocalteau assay where results are reported in gallic acid equivalents.[Cayman Chemical] |
| Biotechnological Production | The production of gallic acid is challenging. Conventionally, it has been produced by acid hydrolysis of tannic acid. However, this process is expensive due to low yields and high impurities. To overcome this problem, microbial production of gallic acid has been suggested. For example, in a solid-state fermentation of Teri pod cover powder containing tannin using Rhizopus oryzae, a yield of 90.9 % based on the tannin content of 58 % of the substrate was observed. In a submerged culture of Aspergillus aceleatus DBF9 growing on a medium with 3 % tannin, a maximal product concentration of 6.8 g.L-1 was reported. With tannic acid, even higher product concentrations of up to 25 g.L-1, a yield of 0.83 g of gallic acid per gram of tannic acid, and a productivity of 0,56 g.L-1.h-1 were shown using Apergillus fischeri MTCC 150 in submerged cultivation. An alternative is the enzymatic hydrolysis of tannic acids using tannase produced by microorganisms (e.g. Aspergillus fischeri or R. oryzae). For example, propyl gallate could be produced using a tannase from Emericela nidulans immobilized on ionic and covalent supports. |
| General Description | Odorless white solid. Sinks in water. |
| Air & Water Reactions | Sparingly water soluble |
| Reactivity Profile | Phenols, such as Gallic acid, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. |
| Health Hazard | Inhalation of dust may irritate nose and throat. Contact with eyes or skin causes irritation. |
| Fire Hazard | Flash point data for Gallic acid are not available. Gallic acid is probably combustible. |
| Purification Methods | Crystallise gallic from water. The tri-O-acetyl derivative has m 172o (from MeOH), and the anilide has m 207o(from EtOH). [Beilstein 10 H 470, 10 IV 1993.] |
| Gallic acid Preparation Products And Raw materials |
| Preparation Products | 3,4,5-TRIETHOXYBENZOIC ACID-->1,2,3-Trimethoxybenzene-->Methyl gallate-->Ethyl gallate-->2,3,4-Trimethoxybenzaldehyde-->2,3,4-Trihydroxybenzaldehyde |
| Raw materials | Glycerite-->Gallic acid monohydrate |